Lung cancer talk, slides and references, with quoted research and links

Lung cancer

The Nervous System
• The nerves that originate from C3-C5 innervate the diaphragm
• Mnemonic for remembering the Innervation of the Lungs:
C3, C4, C5 Keep you Alive!

Smoking and Vitamin Deficiencies
• Research has shown that smokers are often very
deficient in a number of essential, protective
nutrients, and a lack of any one of them could lead to
various disease states, especially lung cancer
Deficiencies caused by smoking:
• Vitamin C
• Vitamin A
•Glutathione

https://www.ncbi.nlm.nih.gov/pubmed/10801913

https://www.ncbi.nlm.nih.gov/pubmed/18565949

https://articles.mercola.com/sites/articles/archive/2009/11/21/do-you-know-the-five-risk-factors-for-lung-cancer-besides-smoking.aspx

Smoking and Vitamin C
•35 percent of the smokers were either marginally or
severely deficient in vitamin C. Even some of those
supplementing with vitamin C were found to be deficient
in vitamin C

American Journal of Public Health

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1349925/

• Exposure to the smoke resulted in progressive protein
damage, inflammation, apoptosis and lung injury.
•However, supplementing with 15 milligrams of vitamin C
per day prevented all of these damaging effects from
occurring

Journal of Inflammation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615750/

Vitamin C
• An antioxidant, helps protect your lungs from free radical
damage, helps regenerate your vitamin E supplies, and
improves iron absorption
• Increase your intake of such vitamin-C-rich foods as citrus
fruits, cantaloupe, strawberries, tomatoes, broccoli,
cabbage, kiwi fruit, sweet red peppers, and potatoes may
exert a protective effect against not only lung problems due to
smoking, but against second-hand smoke as well.
Vitamin A
• An important vitamin for healthy vision, immune system function, and
cell growth.
• It works synergistically with a number of other vitamins and minerals,
including vitamins D, K2, zinc, and magnesium, without which it cannot
perform its functions.
2 main categories of Vitamin A
• Retinoids (fat-soluble, biologically active vitamin A found in animal
foods)
• Carotenoids (water-soluble pro-vitamins found in plant foods)
oCarotenes
oXanthophylls
Retinoids
•Retinol: Bioactive form of vitamin A, which is converted
into retinal, retinoic acid, and retinyl esters
•Retinal: Vision health and healthy growth
•Retinoic acid: Skin health, tooth remineralization, bone
growth
Carotenoids
Carotenes
• Alpha-carotene: Antioxidant with potential anti-cancer activity;
stimulates intercellular communication
Xanthophylls
• Astaxanthin: High-potency antioxidant with anti-inflammatory
properties, shown to benefit rheumatoid arthritis; athletic
performance; heart- and brain health; age-related macular
degeneration. Also protects cells from UV radiation
• Beta-cryptoxanthin: Antioxidant with anti-cancer activity.
Studies show it may reduce risk of lung- and colon cancer by
30 percent, and rheumatoid arthritis by 41 percent
Sources for Bioavailable Vitamin A (Retinoids)
• Pasture-raised beef or duck liver
• Eggs from organic pastured chickens
• Raw organic Butter and cheese from grass-fed cows
• Whole raw milk and heavy cream from organic grass-fed
cows
• Shrimp
• Fatty fish like sardines
Pro-vitamin A Carotenoid-rich foods
• Carrots
• Sweet Potatoes
• Kale
• Spinach
• Butternut squash
• Mustard greens and collard greens

http://articles.mercola.com/sites/articles/archive/2015/11/16/vitamin-a-types.aspx
References

https://www.ncbi.nlm.nih.gov/pubmed/14704326

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242165/

https://www.ncbi.nlm.nih.gov/pubmed/10731492

Glutathione
• Master antioxidant
• Main detoxification system
Food Sources:
• Whey Protein
• Sulfur rich compounds (cruciferous family)
“Glutathione is a vital intracellular and extracellular
protective pulmonary antioxidant. It plays a key role in
regulating oxidant-induced lung epithelial cell function
and also in the control of pro-inflammatory processes.”
(Annals of Allergy, Asthma and Immunology )

https://www.annallergy.org/article/S1081-1206(10)61783-8/abstract

Isothiocyanate and Cancer
• A phytonutrient known for its potent anti-cancer
activity
“Cruciferous vegetables such as cabbage and near
relatives of cabbage such as broccoli and
cauliflower…contain compounds called
isothiocyanates which we believe to be responsible
for the cancer-preventive and anticarcinogenic
activities in these vegetables.”

Sources of Isothiocyanate:
• Broccoli and broccoli sprouts
• Brussel sprouts
• Cauliflower
• Cabbage
• Arugula
• Watercress
•Horseradish
“Broccoli and broccoli sprouts have the highest amount
of the isothiocyanates”

Journal of Carcinogenesis

https://www.ncbi.nlm.nih.gov/pubmed/18952594

Curcumin
• A derivative of turmeric and the pigment that gives its yellow-orange
color
Curcumin and Cancer
•Inhibit the proliferation of tumor cells
•Inhibit the transformation of cells from normal to tumor
• Help the body destroy mutated cancer cells so they
cannot spread throughout the body
• Decrease inflammation
• Help prevent the development of additional blood
supply necessary for cancer cell growth (angiogenesis)

Curcumin and Lung Cancer
• Curcumin inhibits lung cancer cell metastasis.
(Journal of Clinical Experimental Metastasis)

https://www.ncbi.nlm.nih.gov/pubmed/11688958

• Curcumin inhibits COPD-like airway inflammation and
lung cancer progression
(Journal of Carcinogenesis)

https://www.ncbi.nlm.nih.gov/pubmed/19793800

• Curcumin can inhibit tumor growth
(Phytotherapy Research Journal)

http://rexresearch.com/curcumin/turmeric.htm

• Curcumin induces programmed cell death in human
non-small cell lung cancer cells.
(International Journal of Cancer Research and Treatment)

https://www.ncbi.nlm.nih.gov/pubmed/20651361

Curcumin and Lung Cancer
“Curcumin is able to exert anti-inflammatory, antiplatelet,
antioxidative, hepatoprotective and antitumor activities,
particularly against cancers of the liver, skin, pancreas,
prostate, ovary, lung and head neck, as well as having a
positive effect in the treatment of arthritis.”
(Journal of Experimental Therapeutic Medicine)

https://www.ncbi.nlm.nih.gov/pubmed/26640527

“Curcumin might be an effective antimetastatic agent with
a mechanism of anti-invasion via the regulation of certain
gene expressions.”
(Journal of Molecular Pharmacology)

https://www.ncbi.nlm.nih.gov/pubmed/14722241

A Healthy Diet and Lung Cancer
Fruit and vegetable consumption and risk of lung cancer: a
dose-response meta-analysis of prospective cohort studies.
(Journal of Lung Cancer)

https://www.ncbi.nlm.nih.gov/pubmed/25747805

“Our analysis indicated that intake of vegetables and fruits may
have a protective effect on lung cancer”
(European Journal of Clinical Nutrition)

https://www.ncbi.nlm.nih.gov/pubmed/25920421

A moderate level of fruit consumption is associated with a
decreased risk of lung cancer
(Journal of Cancer Science)

http://www.ncbi.nlm.nih.gov/pubmed/26033436

A Healthy Diet and Lung Cancer
Consumption of a diet rich in cruciferous vegetables may
reduce the risk of lung cancer among smokers.
(BMC Cancer)

http://www.ncbi.nlm.nih.gov/pubmed/20423504

Intakes of green leafy vegetables, β-carotene-rich
vegetables, watermelon, vitamin A, and carotenoids
were each inversely associated with lung cancer risk
(Nutrition and Cancer Journal)

https://www.ncbi.nlm.nih.gov/pubmed/23368913

Black Seed
Over 800 published, peer reviewed studies proving the
benefits of Black Seed including:19
• Analgesic (pain killing)
• Anti-Bacterial
• Anti-Inflammatory
• Anti-Ulcer
• Anti-Fungal
• Antioxidant
• Antiviral
Source 20
• Bronchodilator
• Gluconeogenesis Inhibitor (AntiDiabetic)

• Insulin Sensitizing
• Hepatoprotective (Liver Protecting)
• Hypotensive
• Interferon Inducer
• Renoprotective (Kidney Protecting)

As before, lots of info, 50 references in all with more information in the video , along with the slides and references from the talk.

https://www.youtube.com/watch?v=g_qEXbqtcPY&t=22s